Whispering gallery resonators offer a versatile platform for manipulating the photonic transmission. Here, we study such a system, including periodically distributed pointlike impurities along the resonator with ring geometry. Based on an exact expression for the transmission probability we obtain here, we demonstrate that the bound states in the continuum (BICs) form from the whispering gallery modes at the high-symmetry momenta in the ring's Brillouin zone. Furthermore, the presence of the inversion symmetry allows for a selective decoupling of resonant states, favoring the BIC generation and, therefore, allowing extra tunability in the optical transmission of the system.

Language disturbances are a core feature of schizophrenia, often studied as a formal thought disorder. The neurobiology of language in schizophrenia has been addressed within the same framework, that language and thought are equivalents considering symptoms and not signs. This review aims to systematically examine published peer-reviewed studies that employed neuroimaging techniques to investigate aberrant brain-language networks in individuals with schizophrenia in relation to linguistic signs.

This article introduces a novel systematic methodology for modeling a class of multidimensional linear mechanical systems that directly allows to obtain their infinite-dimensional port-Hamiltonian representation. While the approach is tailored to systems governed by specific kinematic assumptions, it encompasses a wide range of models found in current literature, including ℓ-dimensional elasticity models (where ℓ = 1, 2, 3), vibrating strings, torsion in circular bars, classical beam and plate models, among others. The methodology involves formulating the displacement field using primary generalized coordinates via a linear algebraic relation. The non-zero components of the strain tensor are then calculated and expressed using secondary generalized coordinates, enabling the characterization of the skew-adjoint differential operator associated with the port-Hamiltonian representation. By applying Hamilton's principle and employing a specially developed integration by parts formula for the considered class of differential operators, the port-Hamiltonian model is directly obtained, along with the definition of boundary inputs and outputs. To illustrate the methodology, the plate modeling process based on Reddy's third-order shear deformation theory is presented as an example. To the best of our knowledge, this is the first time that a port-Hamiltonian representation of this system is presented in the literature.

This study presents a benchmark of two physics-guided neural surrogates – PhyCNN and multi–LSTM – across three single-degree-of-freedom system scenarios of increasing nonlinearity: (I) a Duffing oscillator; (II) a hysteretic Bouc–Wen system under band-limited noise; and (III) a hysteretic Bouc–Wen isolator representative of base-isolated buildings subjected to long duration Chilean earthquakes. Physics-guided LSTMs achieve the lowest errors in displacement and velocity and better reproduce hysteretic geometry; CNNs yield tighter, more stable errors when the normalized internal force is predicted directly. Reconstructing force from LSTM velocity closes much of the gap but remains fragile in long, strongly nonlinear records due to residual-drift accumulation. Simple training discipline—input/target normalization, validation-driven early stopping and scheduling, and light force regularization—substantially improves robustness.

In the framework of asset management, the effectiveness of an integrated process that manages reliability and maintenance should be adequately and timely evaluated based on a thorough analysis of a series of contributing factors, which should respond entirely to the result of maintenance activities on the performance of assets that make up the production process. According to the above, then arises the motivation for the design and application of tools to determine the effectiveness of such activities in asset management, understanding the latter as a holistic process that involves a diversity of functions and areas within an organization

The utilization of porous biomedical implants featuring a bimodal microstructure has garnered substantial interest within the scientific community. This study delves into the intricate interplay between processing parameters, microstructural attributes, and the tribo-mechanical performance of titanium grade 4, showcasing its potential to serve as implants to address compromised cortical bone tissue. The investigation meticulously examines the impact of milling duration (10 and 20 h), proportion of milled powder (50 and 75 wt%), and the volume fraction of space-holding agents (40–60 vol% NaCl) on the resulting characteristics of the bimodal microstructure, which plays a crucial role in achieving optimal biomechanical equilibrium. The Vickers microhardness, conventional and instrumented (P-h curves), and the wear behavior (ball-on disk) are discussed in terms of bimodal microstructure distribution, particle size and porosity level inherent to the fabrication conditions (mechanical milling + space-holder + hot-pressing). In general terms, milling time and milled powder fraction were the most influent parameters on the final properties of the materials. With the processing route used, the achieved microhardness values and wear behavior are comparable with those obtained by means of surface modifications or alloys. The Young's moduli obtained were in the range of 30–50 GPa, which could help to reduce the shielding phenomenon, while presenting a good mechanical resistance and wear behavior. In light of these findings, the fabricated specimen, composed of 75 wt% milled powder subjected to a 10-h milling duration, supplemented by a 60 vol% fraction of NaCl, emerges as a prime candidate manifesting superior biomechanical equilibrium. This judicious configuration exhibits a promising trajectory for its application in bone replacement endeavors.

Vanillin, o-vanillin, natural and synthetic benzaldehydes and benzyl alcohols were assessed for antiproliferative effects using different human cell lines. Benzyl alcohols were synthesized from benzaldehydes reduced with NaBH4 in methanol solution. A new method for deprotection of ether compounds with TiCl4 solution was achieved with better performance, than previously reported. Twenty four compounds were tested. The in vitro growth inhibition assay was based on sulphorhodamine dye to quantify cell viability. Catechol 9 derived from piperonal as well as compounds 4 and 12 showed higher cytotoxicity on breast and prostate cancer cell lines (MDA-MB-231 and PC-3 respectively). o-Vanillin 5 has the highest cytotoxicity for all cell lines. IC50 values of 35.40 ± 4.2 μM Breast MDA-MB231; 47.10 ± 3.8 μM Prostate PC-3; 72.50 + 5.4 μM Prostate DU-145; 85.10 + 6.5 μM and Colon HT-29, were obtained without toxicity towards dermal human fibroblast (DHF cells).