Structural and computational supported development of 2,5-disubstituted-1,3,4-oxadiazole analogues as active LOX, urease, and α-glucosidase inhibitors

A series of N-substituted analogues of 1,3,4-oxadiazole were synthesized and screened for their enzyme inhibitory activity against lipoxygenase, alpha-glucosidase, and urease enzymes. Spectroscopy studies including IR, C-13-NMR, and H-1-NMR techniques wer